Martha Kent injures mind-reading Ryan in an auto accident, and he fakes amnesia to get away from his criminal step-parents. His step-parents hatch an elaborate plan to steal him back and use his abilities to rob Lex Luthor.

After stealing an experimental flower laced with meteor-rock pollen from Dr. Steven Hamilton, the employee of the Luthor Corp, James Beales has a truck accident on the road and is rescued by Jonathan Kent. However, the flower releases its pollen on Jonathan’s face, and he unleashes his innermost repressed desires first with Martha and his anger towards the Luthors. He enters in coma later. Then Lana becomes affected and tries to seduce Clark. Pete also becomes affected by the Nicodemus flower in the same way. While Clark helps Lex track down the source, Lex hides from Clark that Dr. Steven Hamilton is working for him, but they find the cure in an old book.

As Lex helps Lana prepare for the re-opening of the Smallville theater, The Talon, as a coffee shop, a man from Lex’s past, named Jude Royce, arrives in town and begins stalking Lex wanting to hold him in conjunction with a shooting death at Club Zero in Metropolis three years ago that Lex may have been responsible for. Meanwhile, Chloe looks into Clark’s past as an adopted child while Martha and Jonathan try to thwart Chloe’s moves.

Depressed from losing his scholarship, Whitney joins a gang of thieves. He gets a kryptonite-laced tattoo and gains the gang’s power of phasing through walls. They rob Luthor mansion and seriously injure Chloe, who is interviewing Lex.